Program
Friday, September 23 | Saturday, September 24 |
Sunday, September 25 |
Monday, September 26
Tentative Program
(September 12, 2016)
The Conference venue is the Key Bridge Marriott, just across the bridge from Washington, DC.
Friday, September 23
| 7:00 am | Registration is Open (Potomac Ballroom pre-function) |
| (All general sessions to be held in Potomac Ballroom) | |
| Pre-Meeting – Clinical Trial Design for Cancer Cachexia |
|
|---|---|
| Chair: Jose Garcia, MD | |
| 8:00 am | Introductory Remarks Jose Garcia, MD GRECC-VA Puget Sound and University of Washington, USA |
| 8:05 am | David Kochanczyk Patient Advocate, Martinsville, Indiana, USA First-person perspectives on pancreatic cancer cachexia from a survivor |
| 8:35 am | Aminah Jatoi, MD Mayo Clinic, USA Primary and secondary endpoints in cancer cachexia trials: Functional and patient reported outcomes |
| 8:55 am | Annemie Schols, PhD Maastricht University, The Netherlands Standard of care interventions in cancer cachexia trials: None, nutrition, exercise and other interventions |
| 9:20 am | Marion Couch, MD, PhD Indiana University, USA Cancer cachexia trials from a surgical oncologist's point of view |
| 9:45-10:15 am | Coffee Break |
| 10:15 am | John Friend, MD Helsinn Therapeutics, USA Clinical trial development for CACS – Industry perspective |
| 10:40 am | Giuseppe Rosano, MD, PhD St George's Hospital Medical School, United Kingdom Regulatory considerations for treatment development in cachexia and sarcopenia |
| 11:05 pm | Panel Discussion |
| 12:15 pm | Closing Remarks from the Chair |
| 12:30 - 1:30 pm | Lunch (Potomac Ballroom pre-function) |
| Conversations about Cancer Cachexia for Patients, Caregivers, Physicians and Scientists | |
| 1:30 - 3:00 pm | Moderator: Marion Couch, MD, PhD (Potomac Ballroom) |
1:30–6:00 pm | Poster Set Up (Francis Scott Key and Georgetown Ballrooms) |
| Session 1 – Introductory Remarks and Keynote Address |
|
| 3:30 pm | Introductory Remarks Denis Guttridge, PhD Ohio State University, USA |
| 3:45 pm | Douglas R. Lowy, MD Director, National Cancer Institute (NCI), USA National Cancer Institute’s role in funding cancer research |
| 4:15 pm | Keynote Address Vickie Baracos, PhD University of Alberta, Canada The concurrent advancement of cancer cachexia science and oncology clinical practice |
| 5:15-5:45 pm | Cutting Edge Science in Cancer Cachexia |
| Saunjoo Yoon – University of Florida, USA David van Dijk – Maastricht University, The Netherlands Brandon VanderVeen – University of South Carolina, USA Victor Laurent, PhD – Helmholtz Zentrum Muenchen, Germany Asmita Mishra, PhD – H. Lee Moffitt Cancer Center, USA Thomas Bodnar – The Ohio State University, USA |
|
| 6:00-8:00 pm | Welcoming Reception (Capital View Ballroom) |
| 8:00–10:00 pm | Poster Viewing (Francis Scott Key and Georgetown Ballrooms) |
Saturday, September 24
| 6:30-8:00 am | Breakfast (Capital View Ballroom) |
| Session 2 – New Models of Cancer Cachexia |
|
|---|---|
| Chair: Vickie Baracos, PhD | |
| 8:00 am | David Bilder, PhD University of California Berkeley, USA Drosophila models of cachexia and other cancer-induced systemic syndromes |
| 8:30 am | Teresa Zimmers, PhD Indiana University, USA Of mice and men and pancreatic cancer cachexia |
| Selected Short Talks | |
| 9:00 am 9:15 am 9:30 am |
Christiano Alves – Harvard Medical School, USA Erin Talbert, PhD – The Ohio State University, USA Andrea Bonetto, PhD – Indiana University, USA |
| 9:45-10:15 am | Coffee Break |
| Session 3 – Mechanisms of Muscle Wasting in Cancer Cachexia: Part I |
|
| Chair: Theresa Guise, MD | |
| 10:15 am | David J. Glass, MD Novartis Institutes for Biomedical Research, USA Mechanisms that cause loss of muscle mass and function, and potential methods to correct these |
| 10:45 am | Daniel L. Marks, MD, PhD Oregon Health & Science University, USA Exosomes as neuroendocrine modulators in cancer cachexia |
| 11:15 am | James Carson, PhD University of South Carolina, USA Cancer regulation of contraction-induced anabolic signaling in skeletal muscle |
| Selected Short Talk | |
| 11:45 pm | Rogier Plas, MSc – Wageningen University, The Netherlands |
| 12:00-12:25 pm | Cutting Edge Science in Cancer Cachexia |
| Masanobu Kanou – Teijin Pharma Ltd, Japan Sophia Liva – The Ohio State University, USA Jie Zhu, PhD – Northwestern University, USA Joseph Rupert – Indiana University School of Medicine, USA Katherine Michaelis – Oregon Health & Science University, USA |
|
| 12:30-1:45 pm | Lunch (Capital View Ballroom) |
| 1:45-4:15 pm | Poster Viewing and Judging (Francis Scott Key and Georgetown Ballrooms) |
| Session 4 – Cross-Talk Pathways in Cancer Cachexia |
|
| Chair: Denis Guttridge, PhD | |
| 4:30 pm | Josep Argilés, PhD University of Barcelona, Spain The adipose-muscle axis in cancer cachexia: An update |
| 5:00 pm | Theresa Guise, MD Indiana University, USA Muscle function matters: Role of the tumor-bone microenvironment in regulating muscle function in cancer |
| Selected Short Talk | |
| 5:30 pm | Mauricio Berriel Diaz, PhD – Helmholtz Center, Germany |
| 5:45-6:00 pm | Refreshment Break |
| 6:00 pm | Jochen Springer, MD University Medical Centre Göttingen, Germany The heart and cancer cachexia |
| Selected Short Talk | |
| 6:30 pm | Kevin Burfeind – Oregon Health & Science University, USA |
Sunday, September 25
| 6:30-8:00 am | Breakfast (Potomac Ballroom pre-function) |
| Session 5 – Mechanisms of Muscle Wasting in Cancer Cachexia: Part II |
|
|---|---|
| Chair: David Glass, MD | |
| 8:00 am | Andrew Judge, PhD University of Florida, USA Novel transcriptional networks causative in cancer-induced muscle wasting |
| 8:30 am | Marco Sandri, MD University of Padova, Italy Novel mechanistic insights in cachexia |
| 9:00 am | Imed Gallouzi, PhD McGill University, Canada Direct activation of AMPK prevents cancer-induced muscle wasting |
| Selected Short Talk | |
| 9:30 am | Rosanna Piccirillo, PhD – IRCCS-Mario Negri Institute for Pharmacological Research, Italy |
| 9:45-10:30 am | Announcement of Poster Winners Coffee Break |
| Session 6 – Analysis of Big Data Sets in Cancer Cachexia |
|
| Chair: Teresa Zimmers, PhD | |
| 10:30 am | Pankaj Kumar Singh, PhD University of Nebraska Medical Center, USA Metabolomic changes in cancer cells regulate their cachectic potential |
| 11:00 am | David Thomas, MD Broad Institute, USA Genome-scale approaches to mediator discovery for cancer cachexia |
| Selected Short Talks | |
| 11:30 am 11:45 am |
Carsten Jacobi, PhD – NIBR; Novartis, Switzerland Rachel Nosacka, BA – University of Florida, USA |
| 12:00-1:00 pm | Lunch (Potomac Ballroom pre-function) |
| Session 7 – Pre-Clinical Therapies |
|
| Chair: Josep Argilés, PhD | |
| 1:00 pm | Paola Costelli, PhD University of Torino, Italy Targeting protein breakdown to improve cancer-associated muscle wasting |
| 1:30 pm | Jose Garcia, MD GRECC-VA Puget Sound and University of Washington, USA Mechanisms of action of ghrelin in cancer cachexia |
| 2:00 pm | Denis Guttridge, PhD Ohio State University, USA Reassessing biomarkers in cancer cachexia |
| Selected Short Talk | |
| 2:30 pm | Paul Gregorevic, PhD – University of Melbourne, Australia |
| 2:45-3:15 pm | Refreshment Break |
| Session 8 – Update: Clinical Trial Results |
|
| Chair: Marion Couch, MD, PhD | |
| 3:15 pm | Marion Couch, MD, PhD Indiana University, USA Summary of pre-meeting: Clinical trial design in cancer cachexia |
| 3:30 pm | Melinda Sheffield Moore, PhD University of Texas Medical Branch, Galveston NCI clinical trial of testosterone to combat cachexia in advanced cancer |
| 4:00 pm | Stephan Von Haehling, MD University of Göttingen, Germany Novel treatment approaches to cancer cachexia: Results from two recent randomized controlled trials using essential amino acids and espindolol |
| Selected Short Talk | |
| 4:30 pm | Joshua Kays, MD – Indiana University School of Medicine, USA |
| 4:45 pm | Maurizio Muscaritoli, MD Sapienza University, Italy Prevalence of malnutrition and cachexia in patients at first medical oncology visit: The PreMiO study |
| 5:15 pm | Closing Remarks Denis Guttridge, PhD Ohio State University, USA |